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The infusion services market is rapidly growing and changing, driven by both clinical and financial factors. From 2025 to 2026, infusion services are projected to grow by an estimated compound annual growth rate (CAGR) of about 8% to 10%¹. Growth is being driven by an aging population, increasing prevalence of chronic diseases and the expanding biologics pipeline and its widening range of indications. Meanwhile, payers are actively steering therapies out of hospital outpatient departments (HOPDs) and into lower-cost settings like ambulatory infusion centers (AICs) and patients’ homes.

Health systems must adapt by rethinking their entire infusion services strategy and consider developing a comprehensive infusion services continuum to maintain continuity of both patient care and revenue from these complex therapies.

These are some of the ways health systems are taking action:

Launching or Expanding AIC Sites

While reimbursement per infusion in AICs is lower than in hospital settings, health systems are increasingly investing in these facilities to maintain revenue and continuity of care for patients who would otherwise be sent to chain-based or independent infusion centers.

Expanding Home Infusion Programs

Thanks to improved portable pumps and growing home health capabilities, certain types of home infusions are safe and even preferred by patients. Health systems that create their own home infusion program or partner with an existing expert can negotiate with payers to keep patients under their care. Additionally, Medicare Advantage is expected to further embrace home infusion beyond the limited Part B services it currently covers.

Utilizing Physician Office Infusions

Directing patients to employed physician groups for in-office infusions can work well for certain specialties, like neurology, rheumatology and gastrointestinal care, where patients can receive their treatments during office visits.

Finding Workarounds or Lobbying for Change to Maintain Control

Clear bagging lets hospitals maintain control over the product and still meet payer demands by having the health system’s pharmacy fill and deliver the prescription internally to the infusion center. Hospital associations in some states have banded together to lobby for laws that ban mandatory white bagging or require exceptions in certain circumstances.

Ready to build a more resilient and scalable infusion strategy? Go deeper in our Second Market Outlook Report with expert Ginger Thorpe, Vice President of Health Systems Strategy and Advisory Services.

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